1YRO

Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn

Summary for 1YRO

Entry DOI	10.2210/pdb1yro/pdb
Related	1NKH 1O0R
Descriptor	ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... (9 entities in total)
Functional Keywords	arg228lys mutation; udp-gal complex, transferase activator-transferase complex, transferase activator/transferase
Biological source	Mus musculus (house mouse) More
Cellular location	Secreted: P29752 Isoform Long: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P08037
Total number of polymer chains	4
Total formula weight	96389.45
Authors	Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. (deposition date: 2005-02-04, release date: 2005-03-22, Last modification date: 2023-08-23)
Primary citation	Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I Biochemistry, 44:3202-3210, 2005 Cited by PubMed: 15736931 DOI: 10.1021/bi0479454 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation