1YRO

Crystal structure of beta14,-galactosyltransferase mutant ARG228Lys in complex with alpha-lactalbumin in the presence of UDP-galactose and Mn

1YRO の概要

• エントリーDOI: 10.2210/pdb1yro/pdb
• 関連するPDBエントリー: 1NKH 1O0R
• 分子名称: ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... (9 entities in total)
• 機能のキーワード: arg228lys mutation; udp-gal complex, transferase activator-transferase complex, transferase activator/transferase
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Secreted: P29752; Isoform Long: Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted: P08037
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 96389.45

構造登録者

Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K. (登録日: 2005-02-04, 公開日: 2005-03-22, 最終更新日: 2023-08-23)

• 主引用文献: Ramakrishnan, B.,Boeggeman, E.,Qasba, P.K.; Mutation of Arginine 228 to Lysine Enhances the Glucosyltransferase Activity of Bovine beta-1,4-Galactosyltransferase I; Biochemistry, 44:3202-3210, 2005; PubMed: 15736931; DOI: 10.1021/bi0479454

実験手法

X-RAY DIFFRACTION (1.9 Å)