1YQM
Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA
Summary for 1YQM
Entry DOI | 10.2210/pdb1yqm/pdb |
Related | 1EBM 1FN7 1KO9 1YQK 1YQL 1YQR |
Descriptor | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(7GU)P*GP*TP*CP*TP*AP*C)-3', N-glycosylase/DNA lyase, ... (5 entities in total) |
Functional Keywords | disulfide crosslinking, 8-oxog analog, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 43704.87 |
Authors | Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L. (deposition date: 2005-02-02, release date: 2005-04-05, Last modification date: 2024-02-14) |
Primary citation | Banerjee, A.,Yang, W.,Karplus, M.,Verdine, G.L. Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434:612-618, 2005 Cited by PubMed: 15800616DOI: 10.1038/nature03458 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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