1YQ7
Human farnesyl diphosphate synthase complexed with risedronate
Summary for 1YQ7
Entry DOI | 10.2210/pdb1yq7/pdb |
Descriptor | Farnesyl pyrophosphate synthetase, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | isoprenoid pathway, cholesterol biosynthesis, bisphosphonate inhibitor, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P14324 |
Total number of polymer chains | 1 |
Total formula weight | 43559.75 |
Authors | Kavanagh, K.L.,Guo, K.,Von delft, F.,Arrowsmith, C.,Sundstrom, M.,Edwards, A.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2005-02-01, release date: 2005-02-22, Last modification date: 2023-10-25) |
Primary citation | Kavanagh, K.L.,Guo, K.,Oppermann, U. Human farnesyl diphosphate complexed with clinical inhibitor risedronate To be Published, |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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