1YPL
X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008
Summary for 1YPL
Entry DOI | 10.2210/pdb1ypl/pdb |
Related | 1YPM |
Descriptor | thrombin light chain, Thrombin heavy chain, Hirudin, ... (7 entities in total) |
Functional Keywords | thrombin, inhibitor complex, barrel, 6 stranded beta-sheet, blood clotting-hydrolase inhibitor complex, blood clotting/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P28504 |
Total number of polymer chains | 3 |
Total formula weight | 34870.90 |
Authors | Fokkens, J.,Radau, G. (deposition date: 2005-01-31, release date: 2006-01-17, Last modification date: 2017-10-11) |
Primary citation | Radau, G.,Fokkens, J. Design and X-ray crystal structures of human thrombin with synthetic cyanopeptide-analogues. Pharmazie, 62:83-88, 2007 Cited by PubMed: 17341023PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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