1YP0
Structure of the steroidogenic factor-1 ligand binding domain bound to phospholipid and a SHP peptide motif
Summary for 1YP0
Entry DOI | 10.2210/pdb1yp0/pdb |
Descriptor | nuclear receptor subfamily 5, group A, member 1, Nuclear receptor subfamily 0, group B, member 2, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total) |
Functional Keywords | ligand dependent nuclear receptor, steroidogenic factor-1, nr5a1, helical sandwich fold, lbd fold, transcription |
Biological source | Mus musculus (house mouse) More |
Cellular location | Nucleus: P33242 Cytoplasm : P97947 |
Total number of polymer chains | 2 |
Total formula weight | 29517.50 |
Authors | Li, Y.,Choi, M.,Cavey, G.,Daugherty, J.,Suino, K.,Kovach, A.,Bingham, N.,Kliewer, S.,Xu, H. (deposition date: 2005-01-28, release date: 2005-04-19, Last modification date: 2024-02-14) |
Primary citation | Li, Y.,Choi, M.,Cavey, G.,Daugherty, J.,Suino, K.,Kovach, A.,Bingham, N.,Kliewer, S.,Xu, H. Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1. Mol.Cell, 17:491-502, 2005 Cited by PubMed: 15721253DOI: 10.1016/j.molcel.2005.02.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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