1YNV

Asp79 makes a large, unfavorable contribution to the stability of RNase Sa

1YNV の概要

• エントリーDOI: 10.2210/pdb1ynv/pdb
• 分子名称: Guanyl-specific ribonuclease Sa, SULFATE ION (3 entities in total)
• 機能のキーワード: conformational stability, electrostatic strain, pka, hydrogen bonds and ion pair., hydrolase
• 由来する生物種: Streptomyces aureofaciens
• 細胞内の位置: Secreted: P05798
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10679.61

構造登録者

Trevino, S.R.,Gokulan, K.,Newsom, S.,Thurlkill, R.L.,Shaw, K.L.,Mitkevich, V.A.,Makarov, A.A.,Sacchettini, J.C.,Scholtz, J.M.,Pace, C.N. (登録日: 2005-01-25, 公開日: 2005-07-19, 最終更新日: 2023-08-23)

• 主引用文献: Trevino, S.R.,Gokulan, K.,Newsom, S.,Thurlkill, R.L.,Shaw, K.L.,Mitkevich, V.A.,Makarov, A.A.,Sacchettini, J.C.,Scholtz, J.M.,Pace, C.N.; Asp79 Makes a Large, Unfavorable Contribution to the Stability of RNase Sa.; J.Mol.Biol., 354:967-978, 2005; PubMed: 16288913; DOI: 10.1016/j.jmb.2005.09.091

実験手法

X-RAY DIFFRACTION (1.2 Å)