1YN7

Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase

Summary for 1YN7

• Entry DOI: 10.2210/pdb1yn7/pdb
• Related: 1YN6
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, 10-mer peptide from RNA-directed RNA polymerase subunit P2, ... (4 entities in total)
• Functional Keywords: mhc class 1, h2-db, influenza a, peptide of acid polymerase, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• Total number of polymer chains: 3
• Total formula weight: 44740.15

Authors

Turner, S.J.,Kedzierska, K.,Komodromou, H.,La Gruta, N.L.,Dunstone, M.A.,Webb, A.I.,Webby, R.,Walden, H.,Xie, W.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C. (deposition date: 2005-01-24, release date: 2005-06-28, Last modification date: 2024-10-30)

• Primary citation: Turner, S.J.,Kedzierska, K.,Komodromou, H.,La Gruta, N.L.,Dunstone, M.A.,Webb, A.I.,Webby, R.,Walden, H.,Xie, W.,McCluskey, J.,Purcell, A.W.,Rossjohn, J.,Doherty, P.C.; Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations; Nat.Immunol., 6:382-389, 2005; PubMed: 15785764; DOI: 10.1038/ni1175

Experimental method

X-RAY DIFFRACTION (2.2 Å)