1YLS

Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene

1YLS の概要

• エントリーDOI: 10.2210/pdb1yls/pdb
• 関連するPDBエントリー: 1YKQ 1YKV
• 分子名称: RNA Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: carbon-carbon bond formation, catalytic mechanism, diels-alder reaction, ribozyme, rna
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 33541.68

構造登録者

Serganov, A.,Keiper, S.,Malinina, L.,Tereshko, V.,Skripkin, E.,Hobartner, C.,Polonskaia, A.,Phan, A.T.,Wombacher, R.,Micura, R.,Dauter, Z.,Jaschke, A.,Patel, D.J. (登録日: 2005-01-19, 公開日: 2005-02-22, 最終更新日: 2024-02-14)

• 主引用文献: Serganov, A.,Keiper, S.,Malinina, L.,Tereshko, V.,Skripkin, E.,Hobartner, C.,Polonskaia, A.,Phan, A.T.,Wombacher, R.,Micura, R.,Dauter, Z.,Jaschke, A.,Patel, D.J.; Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.; Nat.Struct.Mol.Biol., 12:218-224, 2005; PubMed: 15723077; DOI: 10.1038/nsmb906

実験手法

X-RAY DIFFRACTION (3 Å)