1YKI

The structure of E. coli nitroreductase bound with the antibiotic nitrofurazone

1YKI の概要

• エントリーDOI: 10.2210/pdb1yki/pdb
• 関連するPDBエントリー: 1ICR 1ICU 1ICV 1YLR 1YLU
• 分子名称: Oxygen-insensitive NAD(P)H nitroreductase, FLAVIN MONONUCLEOTIDE, NITROFURAZONE, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, oxygen-insensitive nad(p)h nitroreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 98793.17

構造登録者

Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I. (登録日: 2005-01-18, 公開日: 2005-02-08, 最終更新日: 2023-08-23)

• 主引用文献: Race, P.R.,Lovering, A.L.,Green, R.M.,Ossor, A.,White, S.A.,Searle, P.F.,Wrighton, C.J.,Hyde, E.I.; Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.; J.Biol.Chem., 280:13256-13264, 2005; PubMed: 15684426; DOI: 10.1074/jbc.M409652200

実験手法

X-RAY DIFFRACTION (1.7 Å)