1YK0

structure of natriuretic peptide receptor-C complexed with atrial natriuretic peptide

Summary for 1YK0

• Entry DOI: 10.2210/pdb1yk0/pdb
• Related: 1YK1
• Descriptor: Atrial natriuretic peptide clearance receptor, Atrial natriuretic factor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hormone-receptor complex, natriuretic peptide receptor, allosteric activation, hormone-growth factor receptor complex, hormone/growth factor receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: P17342; Secreted: P01160
• Total number of polymer chains: 3
• Total formula weight: 109133.76

Authors

He, X.,Garcia, K.C. (deposition date: 2005-01-16, release date: 2006-04-18, Last modification date: 2023-08-23)

• Primary citation: He, X.L.,Dukkipati, A.,Garcia, K.C.; Structural determinants of natriuretic peptide receptor specificity and degeneracy.; J.Mol.Biol., 361:698-714, 2006; PubMed: 16870210; DOI: 10.1016/j.jmb.2006.06.060

Experimental method

X-RAY DIFFRACTION (2.4 Å)