1YJW

Crystal Structure Of Quinupristin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui

Summary for 1YJW

Entry DOI	10.2210/pdb1yjw/pdb
Related	1YHQ 1YI2 1YIT
Related PRD ID	PRD_000505
Descriptor	23S RIBOSOMAL RNA, 50S ribosomal protein L5, 50S ribosomal protein L6, ... (38 entities in total)
Functional Keywords	quinupristin, dalfopristin, streptogramin, antibiotic, mutated 50s subunits, ribosome, ribosome-antibiotic complex, ribosome/antibiotic
Biological source	Haloarcula marismortui More
Cellular location	Cytoplasm : P20279
Total number of polymer chains	32
Total formula weight	1481592.84
Authors	Tu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A. (deposition date: 2005-01-15, release date: 2005-04-26, Last modification date: 2023-06-14)
Primary citation	Tu, D.,Blaha, G.,Moore, P.B.,Steitz, T.A. Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance. Cell(Cambridge,Mass.), 121:257-, 2005 Cited by PubMed: 15851032 DOI: 10.1016/J.CELL.2005.02.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation