1YHJ

Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives

Summary for 1YHJ

Entry DOI	10.2210/pdb1yhj/pdb
Descriptor	Pyridoxal Kinase, (2R)-2-{[6-(BENZYLOXY)-9-ISOPROPYL-9H-PURIN-2-YL]AMINO}BUTAN-1-OL (3 entities in total)
Functional Keywords	alpha-beta structure, complexed with o6-(r)-roscovitine, transferase
Biological source	Ovis aries (sheep)
Cellular location	Cytoplasm: P82197
Total number of polymer chains	1
Total formula weight	35216.31
Authors	Tang, L.,Li, M.-H.,Cao, P.,Wang, F.,Chang, W.-R.,Bach, S.,Reinhardt, J.,Ferandin, Y.,Koken, M.,Galons, H.,Wan, Y.,Gray, N.,Meijer, L.,Jiang, T.,Liang, D.-C. (deposition date: 2005-01-09, release date: 2005-07-05, Last modification date: 2024-03-13)
Primary citation	Tang, L.,Li, M.-H.,Cao, P.,Wang, F.,Chang, W.-R.,Bach, S.,Reinhardt, J.,Ferandin, Y.,Galons, H.,Wan, Y.,Gray, N.,Meijer, L.,Jiang, T.,Liang, D.-C. Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. J.Biol.Chem., 280:31220-31229, 2005 Cited by PubMed: 15985434 DOI: 10.1074/jbc.M500805200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation