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1YGS

CRYSTAL STRUCTURE OF THE SMAD4 TUMOR SUPPRESSOR C-TERMINAL DOMAIN

Summary for 1YGS
Entry DOI10.2210/pdb1ygs/pdb
DescriptorSMAD4 (2 entities in total)
Functional Keywordssmad4, tumor suppressor c-terminal domain, tgf-beta signal mediator, beta-sandwich scaffold with a three-helix bundle, tumour suppressor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: Q13485
Total number of polymer chains1
Total formula weight25511.09
Authors
Shi, Y.,Hata, A.,Lo, R.S.,Massague, J.,Pavletich, N.P. (deposition date: 1997-10-03, release date: 1998-07-08, Last modification date: 2024-02-14)
Primary citationShi, Y.,Hata, A.,Lo, R.S.,Massague, J.,Pavletich, N.P.
A structural basis for mutational inactivation of the tumour suppressor Smad4.
Nature, 388:87-93, 1997
Cited by
PubMed: 9214508
DOI: 10.1038/40431
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217157

数据于2024-03-13公开中

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