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1YER

HUMAN HSP90 GELDANAMYCIN-BINDING DOMAIN, "CLOSED" CONFORMATION

Summary for 1YER
Entry DOI10.2210/pdb1yer/pdb
DescriptorHEAT SHOCK PROTEIN 90 (2 entities in total)
Functional Keywordschaperone protein, geldanamycin, signal transduction, heat shock
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P07900
Total number of polymer chains1
Total formula weight25670.79
Authors
Stebbins, C.E.,Russo, A.A.,Pavletich, N.P. (deposition date: 1997-03-25, release date: 1998-04-22, Last modification date: 2024-02-14)
Primary citationStebbins, C.E.,Russo, A.A.,Schneider, C.,Rosen, N.,Hartl, F.U.,Pavletich, N.P.
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent.
Cell(Cambridge,Mass.), 89:239-250, 1997
Cited by
PubMed: 9108479
DOI: 10.1016/S0092-8674(00)80203-2
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

217705

數據於2024-03-27公開中

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