1Y77

Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP

Summary for 1Y77

• Entry DOI: 10.2210/pdb1y77/pdb
• Related: 1Y1W
• Descriptor: 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*T*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*G)-3', DNA-directed RNA polymerase II 19 kDa polypeptide, DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide, ... (18 entities in total)
• Functional Keywords: transcription, substrate, ntp, elongation, transferase-dna-rna hybrid complex, transferase/dna-rna hybrid
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Cellular location: Nucleus: P04050 P38902 P08518 P16370 P20433 P20434 P34087 P20436 P27999; Nucleus, nucleolus: P22139 P40422; Cytoplasm: P20435
• Total number of polymer chains: 15
• Total formula weight: 526383.23

Authors

Kettenberger, H.,Armache, K.-J.,Cramer, P. (deposition date: 2004-12-08, release date: 2005-01-04, Last modification date: 2023-10-25)

• Primary citation: Kettenberger, H.,Armache, K.-J.,Cramer, P.; Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS; Mol.Cell, 16:955-965, 2004; PubMed: 15610738; DOI: 10.1016/j.molcel.2004.11.040

Experimental method

X-RAY DIFFRACTION (4.5 Å)