1Y6Q

Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA

1Y6Q の概要

• エントリーDOI: 10.2210/pdb1y6q/pdb
• 分子名称: MTA/SAH nucleosidase, CHLORIDE ION, (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, ... (4 entities in total)
• 機能のキーワード: mixed alpha/beta dimer, hydrolase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 51633.93

構造登録者

Lee, J.E.,Singh, V.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Cornell, K.A.,Riscoe, M.K.,Schramm, V.L.,Howell, P.L. (登録日: 2004-12-06, 公開日: 2005-03-01, 最終更新日: 2023-08-23)

• 主引用文献: Lee, J.E.,Singh, V.,Evans, G.B.,Tyler, P.C.,Furneaux, R.H.,Cornell, K.A.,Riscoe, M.K.,Schramm, V.L.,Howell, P.L.; Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.; J.Biol.Chem., 280:18274-18282, 2005; PubMed: 15746096; DOI: 10.1074/jbc.M414471200

実験手法

X-RAY DIFFRACTION (2.2 Å)