1Y1D
Crystal structure of transthyretin in complex with iododiflunisal
Summary for 1Y1D
Entry DOI | 10.2210/pdb1y1d/pdb |
Descriptor | Transthyretin, 2',4'-DIFLUORO-4-HYDROXY-5-IODO-1,1'-BIPHENYL-3-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | transthyretin, amyloid, iododiflunisal, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02766 |
Total number of polymer chains | 2 |
Total formula weight | 28306.91 |
Authors | Gales, L.,Macedo-Ribeiro, S.,Arsequell, G.,Valencia, G.,Saraiva, M.J.,Damas, A.M. (deposition date: 2004-11-18, release date: 2005-07-26, Last modification date: 2023-08-23) |
Primary citation | Gales, L.,Macedo-Ribeiro, S.,Arsequell, G.,Valencia, G.,Saraiva, M.J.,Damas, A.M. Human transthyretin in complex with iododiflunisal: structural features associated with a potent amyloid inhibitor. Biochem.J., 388:615-621, 2005 Cited by PubMed: 15689188DOI: 10.1042/BJ20042035 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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