1XWS
Crystal Structure of the human PIM1 kinase domain
Summary for 1XWS
Entry DOI | 10.2210/pdb1xws/pdb |
Descriptor | Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION, 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, ... (4 entities in total) |
Functional Keywords | pim1, kinase, cancer, leukemia, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309 |
Total number of polymer chains | 1 |
Total formula weight | 36241.29 |
Authors | Knapp, S.,Debreczeni, J.,Bullock, A.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Guo, K. (deposition date: 2004-11-02, release date: 2004-11-16, Last modification date: 2024-03-13) |
Primary citation | Knapp, S.,Debreczeni, J.,Bullock, A.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.,Edwards, A.,Guo, K. Crystal structure of human PIM1 kinase domain To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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