1XWL

BACILLUS STEAROTHERMOPHILUS (NEWLY IDENTIFIED STRAIN AS YET UNNAMED) DNA POLYMERASE FRAGMENT

Replaces:  1BDP

Summary for 1XWL

• Entry DOI: 10.2210/pdb1xwl/pdb
• Descriptor: DNA POLYMERASE I, SULFATE ION (3 entities in total)
• Functional Keywords: bacillus stearothermophilus dna polymerase, bf thermophilus polymerase, dna replication
• Biological source: Geobacillus stearothermophilus
• Total number of polymer chains: 1
• Total formula weight: 66364.97

Authors

Kiefer, J.R.,Mao, C.,Beese, L.S. (deposition date: 1998-07-22, release date: 1999-01-13, Last modification date: 2024-05-22)

Primary citation

Kiefer, J.R.,Mao, C.,Hansen, C.J.,Basehore, S.L.,Hogrefe, H.H.,Braman, J.C.,Beese, L.S.
Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 A resolution.
Structure, 5:95-108, 1997

PubMed Abstract: The study of DNA polymerases in the Pol l family is central to the understanding of DNA replication and repair. DNA polymerases are used in many molecular biology techniques, including PCR, which require a thermostable polymerase. In order to learn about Pol I function and the basis of thermostability, we undertook structural studies of a new thermostable DNA polymerase.

PubMed: 9016716
DOI: 10.1016/S0969-2126(97)00169-X

Experimental method

X-RAY DIFFRACTION (1.7 Å)