1XWH

NMR structure of the first phd finger of autoimmune regulator protein (AIRE1): insights into apeced

Summary for 1XWH

• Entry DOI: 10.2210/pdb1xwh/pdb
• NMR Information: BMRB: 6374
• Descriptor: Autoimmune regulator, ZINC ION (2 entities in total)
• Functional Keywords: phd domain, zn binding domain, apeced, nucleosome, e3 ligase, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O43918
• Total number of polymer chains: 1
• Total formula weight: 7275.92

Authors

Bottomley, M.J.,Stier, G.,Krasotkina, J.,Legube, G.,Simon, B.,Akhtar, A.,Sattler, M.,Musco, G. (deposition date: 2004-11-01, release date: 2005-01-25, Last modification date: 2022-03-02)

• Primary citation: Bottomley, M.J.,Stier, G.,Pennacchini, D.,Legube, G.,Simon, B.,Akhtar, A.,Sattler, M.,Musco, G.; NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1). Insights into autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) disease; J.Biol.Chem., 280:11505-11512, 2005; PubMed: 15649886; DOI: 10.1074/jbc.M413959200

Experimental method

SOLUTION NMR