1XRS

Crystal structure of Lysine 5,6-Aminomutase in complex with PLP, cobalamin, and 5'-deoxyadenosine

1XRS の概要

• エントリーDOI: 10.2210/pdb1xrs/pdb
• 分子名称: D-lysine 5,6-aminomutase alpha subunit, D-lysine 5,6-aminomutase beta subunit, COBALAMIN, ... (5 entities in total)
• 機能のキーワード: tim barrel, rossmann domain, plp, cobalamin, b12, 5'-deoxyadenosine, radical, mutase, adenosylcobalamin, conformational change, isomerase
• 由来する生物種: Clostridium sticklandii; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88467.28

構造登録者

Berkovitch, F.,Behshad, E.,Tang, K.H.,Enns, E.A.,Frey, P.A.,Drennan, C.L. (登録日: 2004-10-15, 公開日: 2004-11-09, 最終更新日: 2017-10-11)

• 主引用文献: Berkovitch, F.,Behshad, E.,Tang, K.H.,Enns, E.A.,Frey, P.A.,Drennan, C.L.; A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase.; Proc.Natl.Acad.Sci.Usa, 101:15870-15875, 2004; PubMed: 15514022; DOI: 10.1073/pnas.0407074101

実験手法

X-RAY DIFFRACTION (2.8 Å)