1XR6

Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B

「1TE8」から置き換えられました

1XR6 の概要

• エントリーDOI: 10.2210/pdb1xr6/pdb
• 関連するPDBエントリー: 1TE8 1TE9 1TEB 1XR5 1XR7
• 分子名称: Genome polyprotein, POTASSIUM ION (3 entities in total)
• 機能のキーワード: rna-dependent rna polymerase, transferase
• 由来する生物種: Human rhinovirus 1B
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P12916
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 52408.08

構造登録者

Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A. (登録日: 2004-10-13, 公開日: 2004-10-26, 最終更新日: 2024-02-14)

• 主引用文献: Love, R.A.,Maegley, K.A.,Yu, X.,Ferre, R.A.,Lingardo, L.K.,Diehl, W.,Parge, H.E.,Dragovich, P.S.,Fuhrman, S.A.; The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy; Structure, 12:1533-1544, 2004; PubMed: 15296746; DOI: 10.1016/j.str.2004.05.024

実験手法

X-RAY DIFFRACTION (2.5 Å)