1XLU

X-Ray Structure Of Di-Isopropyl-Phosphoro-Fluoridate (Dfp) Inhibited Butyrylcholinesterase after Aging

Summary for 1XLU

• Entry DOI: 10.2210/pdb1xlu/pdb
• Related: 1POI 1POM 1POP 1POQ 1XLV 1XLW
• Descriptor: BUTYRYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: cholinesterase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 62271.69

Authors

Nachon, F.,Asojo, O.A.,Borgstahl, G.E.O.,Masson, P.,Lockridge, O. (deposition date: 2004-09-30, release date: 2005-02-01, Last modification date: 2023-11-15)

• Primary citation: Nachon, F.,Asojo, O.A.,Borgstahl, G.E.O.,Masson, P.,Lockridge, O.; Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging; Biochemistry, 44:1154-1162, 2005; PubMed: 15667209; DOI: 10.1021/bi048238d

Experimental method

X-RAY DIFFRACTION (2.198 Å)