1XLU

X-Ray Structure Of Di-Isopropyl-Phosphoro-Fluoridate (Dfp) Inhibited Butyrylcholinesterase after Aging

1XLU の概要

• エントリーDOI: 10.2210/pdb1xlu/pdb
• 関連するPDBエントリー: 1POI 1POM 1POP 1POQ 1XLV 1XLW
• 分子名称: BUTYRYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: cholinesterase, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 62271.69

構造登録者

Nachon, F.,Asojo, O.A.,Borgstahl, G.E.O.,Masson, P.,Lockridge, O. (登録日: 2004-09-30, 公開日: 2005-02-01, 最終更新日: 2023-11-15)

• 主引用文献: Nachon, F.,Asojo, O.A.,Borgstahl, G.E.O.,Masson, P.,Lockridge, O.; Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging; Biochemistry, 44:1154-1162, 2005; PubMed: 15667209; DOI: 10.1021/bi048238d

実験手法

X-RAY DIFFRACTION (2.198 Å)