1XFW

Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3'5' cyclic AMP (cAMP)

Summary for 1XFW

• Entry DOI: 10.2210/pdb1xfw/pdb
• Related: 1XFU 1XFV 1XFX 1XFY 1XFZ
• Descriptor: Calmodulin-sensitive adenylate cyclase, Calmodulin 2, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: protein-protein interaction, lyase-metal binding protein complex, lyase/metal binding protein
• Biological source: Bacillus anthracis; More
• Cellular location: Secreted: P40136
• Total number of polymer chains: 12
• Total formula weight: 644725.22

Authors

Shen, Y.,Zhukovskaya, N.L.,Guo, Q.,Florian, J.,Tang, W.J. (deposition date: 2004-09-15, release date: 2005-05-03, Last modification date: 2024-02-14)

• Primary citation: Shen, Y.,Zhukovskaya, N.L.,Guo, Q.,Florian, J.,Tang, W.J.; Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.; EMBO J., 24:929-941, 2005; PubMed: 15719022; DOI: 10.1038/sj.emboj.7600574

Experimental method

X-RAY DIFFRACTION (3.4 Å)