1XD1

Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts

Summary for 1XD1

Entry DOI	10.2210/pdb1xd1/pdb
Related	1XCW 1XCX 1XD0
Descriptor	Alpha-amylase, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACARBOSE DERIVED HEXASACCHARIDE, ... (6 entities in total)
Functional Keywords	amylase, acarbose, acarbose analogues, inhibitor, acarviosine, isoacarbose, enzyme, catalysis, enzyme mechanism, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	57197.93
Authors	Li, C.,Begum, A.,Numao, S.,Park, K.H.,Withers, S.G.,Brayer, G.D. (deposition date: 2004-09-03, release date: 2004-12-07, Last modification date: 2020-07-29)
Primary citation	Li, C.,Begum, A.,Numao, S.,Park, K.H.,Withers, S.G.,Brayer, G.D. Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts Biochemistry, 44:3347-3357, 2005 Cited by PubMed: 15736945 DOI: 10.1021/bi048334e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation