1XCS

structure of oligonucleotide/drug complex

Summary for 1XCS

• Entry DOI: 10.2210/pdb1xcs/pdb
• Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3', COBALT (II) ION, 9-[(5-(ACETYLAMINO)-6-{[(1S,4R)-8-AMINO-4-[((2R)-6-AMINO-2-{2-[(1S)-5-AMINO-1-FORMYLPENTYL]HYDRAZINO}HEXANOYL)AMINO]-1-(4-AMINOBUTYL)-2,3-DIOXOOCTYL]AMINO}-6-OXOHEXYL)AMINO]-6-CHLORO-2-METHOXYACRIDINIUM, ... (5 entities in total)
• Functional Keywords: drug-dna complex, double helix, co2+, dna
• Total number of polymer chains: 2
• Total formula weight: 4801.22

Authors

Valls, N.,Steiner, R.A.,Wright, G.,Murshudov, G.N.,Subirana, J.A. (deposition date: 2004-09-03, release date: 2005-07-19, Last modification date: 2024-02-14)

• Primary citation: Valls, N.,Steiner, R.A.,Wright, G.,Murshudov, G.N.,Subirana, J.A.; Variable role of ions in two drug intercalation complexes of DNA; J.Biol.Inorg.Chem., 10:476-482, 2005; PubMed: 15926069; DOI: 10.1007/s00775-005-0655-3

Experimental method

X-RAY DIFFRACTION (1.4 Å)