1XCG

Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF

1XCG の概要

• エントリーDOI: 10.2210/pdb1xcg/pdb
• 分子名称: Rho guanine nucleotide exchange factor 11, Transforming protein RhoA (3 entities in total)
• 機能のキーワード: x-ray crystallography; regulation of rhoa gtpase; protein complex, signaling protein activator-signaling protein complex, signaling protein activator/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: O15085; Cell membrane; Lipid-anchor; Cytoplasmic side: P61586
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 125875.00

構造登録者

Derewenda, U.,Oleksy, A.,Stevenson, A.S.,Korczynska, J.,Dauter, Z.,Somlyo, A.P.,Otlewski, J.,Somlyo, A.V.,Derewenda, Z.S. (登録日: 2004-09-01, 公開日: 2004-12-14, 最終更新日: 2024-02-14)

• 主引用文献: Derewenda, U.,Oleksy, A.,Stevenson, A.S.,Korczynska, J.,Dauter, Z.,Somlyo, A.P.,Otlewski, J.,Somlyo, A.V.,Derewenda, Z.S.; The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle; Structure, 12:1955-1965, 2004; PubMed: 15530360; DOI: 10.1016/j.str.2004.09.003

実験手法