1XAR
Crystal Structure of a fragment of DC-SIGNR (containing the carbohydrate recognition domain and two repeats of the neck).
Summary for 1XAR
Entry DOI | 10.2210/pdb1xar/pdb |
Descriptor | CD209 antigen-like protein 1, SODIUM ION (3 entities in total) |
Functional Keywords | dc-signr, c-type lectin, sugar binding protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 2: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 3: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 5: Secreted (Potential). Isoform 6: Secreted (Potential). Isoform 7: Secreted (Potential). Isoform 10: Secreted (Potential): Q9H2X3 |
Total number of polymer chains | 2 |
Total formula weight | 42900.97 |
Authors | Feinberg, H.,Guo, Y.,Mitchell, D.A.,Drickamer, K.,Weis, W.I. (deposition date: 2004-08-26, release date: 2004-11-16, Last modification date: 2011-07-13) |
Primary citation | Feinberg, H.,Guo, Y.,Mitchell, D.A.,Drickamer, K.,Weis, W.I. Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR J.Biol.Chem., 280:1327-1335, 2005 Cited by PubMed: 15509576DOI: 10.1074/jbc.M409925200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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