1XAH

CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+ AND NAD+

1XAH の概要

• エントリーDOI: 10.2210/pdb1xah/pdb
• 関連するPDBエントリー: 1NR5 1NRX 1NUA 1NVA 1NVB 1NVD 1NVE 1NVF 1XAG 1XAI 1XAJ 1XAL
• 分子名称: 3-dehydroquinate synthase, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: shikimate pathway, aromatic amino acid biosynthesis, dhqs, sadhqs, open form, form b, domain movement, cyclase, lyase
• 由来する生物種: Staphylococcus aureus
• 細胞内の位置: Cytoplasm (Probable): Q6GGU4
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82175.46

構造登録者

Nichols, C.E.,Ren, J.,Leslie, K.,Dhaliwal, B.,Lockyer, M.,Charles, I.,Hawkins, A.R.,Stammers, D.K. (登録日: 2004-08-25, 公開日: 2005-03-01, 最終更新日: 2023-08-23)

• 主引用文献: Nichols, C.E.,Ren, J.,Leslie, K.,Dhaliwal, B.,Lockyer, M.,Charles, I.,Hawkins, A.R.,Stammers, D.K.; Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases.; J.Mol.Biol., 343:533-546, 2004; PubMed: 15465043; DOI: 10.1016/j.jmb.2004.08.039

実験手法

X-RAY DIFFRACTION (2.2 Å)