1XAG

CRYSTAL STRUCTURE OF STAPHLYOCOCCUS AUREUS 3-DEHYDROQUINATE SYNTHASE (DHQS) IN COMPLEX WITH ZN2+, NAD+ AND CARBAPHOSPHONATE

Summary for 1XAG

Entry DOI	10.2210/pdb1xag/pdb
Related	1NR5 1NRX 1NUA 1NVA 1NVB 1NVD 1NVE 1NVF 1XAH 1XAI 1XAJ 1XAL
Descriptor	3-dehydroquinate synthase, ZINC ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	shikimate pathway, aromatic amino acid biosynthesis, dhqs, sadhqs, closed form, form a, domain movement, cyclase, lyase
Biological source	Staphylococcus aureus
Cellular location	Cytoplasm (Probable): Q6GGU4
Total number of polymer chains	1
Total formula weight	41535.17
Authors	Nichols, C.E.,Ren, J.,Leslie, K.,Dhaliwal, B.,Lockyer, M.,Charles, I.,Hawkins, A.R.,Stammers, D.K. (deposition date: 2004-08-25, release date: 2005-03-01, Last modification date: 2023-08-23)
Primary citation	Nichols, C.E.,Ren, J.,Leslie, K.,Dhaliwal, B.,Lockyer, M.,Charles, I.,Hawkins, A.R.,Stammers, D.K. Comparison of ligand induced conformational changes and domain closure mechanisms, between prokaryotic and eukaryotic dehydroquinate synthases. J.Mol.Biol., 343:533-546, 2004 Cited by PubMed: 15465043 DOI: 10.1016/j.jmb.2004.08.039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation