1X9Q

4m5.3 anti-fluorescein single chain antibody fragment (scFv)

1X9Q の概要

• エントリーDOI: 10.2210/pdb1x9q/pdb
• 分子名称: 4m5.3 anti-fluorescein single chain antibody fragment, ACETATE ION, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, ... (4 entities in total)
• 機能のキーワード: very high affinity, antibody binding, electrostatics, directed evolution, single chain antibody, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30110.27

構造登録者

Midelfort, K.S.,Hernandez, H.H.,Lippow, S.M.,Tidor, B.,Drennan, C.L.,Wittrup, K.D. (登録日: 2004-08-24, 公開日: 2005-03-22, 最終更新日: 2023-08-23)

• 主引用文献: Midelfort, K.S.,Hernandez, H.H.,Lippow, S.M.,Tidor, B.,Drennan, C.L.,Wittrup, K.D.; Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody; J.Mol.Biol., 343:685-701, 2004; PubMed: 15465055; DOI: 10.1016/j.jmb.2004.08.019

実験手法

X-RAY DIFFRACTION (1.5 Å)