1X9M
T7 DNA polymerase in complex with an N-2-acetylaminofluorene-adducted DNA
Summary for 1X9M
Entry DOI | 10.2210/pdb1x9m/pdb |
Related | 1T7P 1X9S 1X9W |
Descriptor | 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*TP*GP*GP*TP*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', 5'-D(*CP*CP*CP*(8FG)P*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', DNA polymerase, ... (6 entities in total) |
Functional Keywords | dna ploymerase, n-2-acetylaminofluorene, replication block, mutagenesis, transferase-electron transport-dna complex, transferase/electron transport/dna |
Biological source | Enterobacteria phage T7 More |
Total number of polymer chains | 4 |
Total formula weight | 105706.24 |
Authors | Dutta, S.,Li, Y.,Johnson, D.,Dzantiev, L.,Richardson, C.C.,Romano, L.J.,Ellenberger, T. (deposition date: 2004-08-23, release date: 2004-10-26, Last modification date: 2024-02-14) |
Primary citation | Dutta, S.,Li, Y.,Johnson, D.,Dzantiev, L.,Richardson, C.C.,Romano, L.J.,Ellenberger, T. Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.USA, 101:16186-16191, 2004 Cited by PubMed: 15528277DOI: 10.1073/pnas.0406516101 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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