1X88

Human Eg5 motor domain bound to Mg-ADP and monastrol

Summary for 1X88

• Entry DOI: 10.2210/pdb1x88/pdb
• Related: 1II6 1Q0B
• Descriptor: Kinesin-like protein KIF11, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: switch ii, motor domain, neck linker, cell cycle
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P52732
• Total number of polymer chains: 2
• Total formula weight: 81851.02

Authors

Maliga, Z.,Mitchison, T.J. (deposition date: 2004-08-17, release date: 2005-11-15, Last modification date: 2024-04-03)

• Primary citation: Maliga, Z.,Mitchison, T.J.; Structural Basis of Eg5 Inhibition by Monastrol; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.8 Å)