1WUG

complex structure of PCAF bromodomain with small chemical ligand NP1

Summary for 1WUG

• Entry DOI: 10.2210/pdb1wug/pdb
• Related: 1B91 1JM4 1WUM
• NMR Information: BMRB: 6508
• Descriptor: Histone acetyltransferase PCAF, N-(3-AMINOPROPYL)-4-METHYL-2-NITROBENZENAMINE (2 entities in total)
• Functional Keywords: bromodomain, histone-acetyltransferase, nmr-structure, chemical ligand, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (By similarity): Q92831
• Total number of polymer chains: 1
• Total formula weight: 14261.47

Authors

Zeng, L.,Li, J.,Muller, M.,Yan, S.,Mujtaba, S.,Pan, C.,Wang, Z.,Zhou, M.M. (deposition date: 2004-12-07, release date: 2005-08-16, Last modification date: 2022-03-02)

• Primary citation: Zeng, L.,Li, J.,Muller, M.,Yan, S.,Mujtaba, S.,Pan, C.,Wang, Z.,Zhou, M.M.; Selective small molecules blocking HIV-1 Tat and coactivator PCAF association; J.Am.Chem.Soc., 127:2376-2377, 2005; PubMed: 15724976; DOI: 10.1021/ja044885g

Experimental method

SOLUTION NMR