1WUA

The structure of Aplyronine A-actin complex

Summary for 1WUA

Entry DOI	10.2210/pdb1wua/pdb
Descriptor	Actin, alpha skeletal muscle, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	aplyronine a, macrolide, potent antitumor effect, marine sponge, structural protein
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Cytoplasm, cytoskeleton: P68135
Total number of polymer chains	1
Total formula weight	43499.34
Authors	Hirata, K.,Muraoka, S.,Suenaga, K.,Kuroda, T.,Kato, K.,Tanaka, H.,Yamamoto, M.,Takata, M.,Yamada, K.,Kigoshi, H. (deposition date: 2004-12-03, release date: 2006-02-14, Last modification date: 2023-10-25)
Primary citation	Hirata, K.,Muraoka, S.,Suenaga, K.,Kuroda, T.,Kato, K.,Tanaka, H.,Yamamoto, M.,Takata, M.,Yamada, K.,Kigoshi, H. Structure basis for antitumor effect of aplyronine a J.Mol.Biol., 356:945-954, 2006 Cited by PubMed: 16406066 DOI: 10.1016/j.jmb.2005.12.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation