1WT2

Mutant human ABO(H) blood group glycosyltransferase A with bound UDP and inhibitor

Summary for 1WT2

Related1WSZ 1WT0 1WT1 1WT3
DescriptorHisto-blood group ABO system transferase, HEXYL 3-DEOXY-BETA-D-GALACTOPYRANOSE, ALPHA-L-FUCOSE, ... (6 entities in total)
Functional Keywordstransferase
Biological sourceHomo sapiens (human)
Cellular locationGolgi apparatus, Golgi stack membrane; Single-pass type II membrane protein P16442
Total number of polymer chains1
Total molecular weight35656.28
Authors
Lee, H.J.,Barry, C.H.,Borisova, S.N.,Seto, N.O.L.,Zheng, R.B.,Blancher, A.,Evans, S.V.,Palcic, M.M. (deposition date: 2004-11-12, release date: 2004-12-07, Last modification date: 2012-06-20)
Primary citation
Lee, H.J.,Barry, C.H.,Borisova, S.N.,Seto, N.O.L.,Zheng, R.B.,Blancher, A.,Evans, S.V.,Palcic, M.M.
Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280:525-529, 2005
PubMed: 15475562 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M410245200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.211110.4%2.6%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution