1WM0

PPARgamma in complex with a 2-BABA compound

1WM0 の概要

• エントリーDOI: 10.2210/pdb1wm0/pdb
• 分子名称: Peroxisome proliferator activated receptor gamma, 14-mer from Nuclear receptor coactivator 2, 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID (3 entities in total)
• 機能のキーワード: three-layer helical domain, transcription-signaling protein complex, transcription/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein (Potential): Q96J12; Nucleus: Q61026
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35382.64

構造登録者

Ostberg, T.,Svensson, S.,Selen, G.,Uppenberg, J.,Thor, M.,Sundbom, M.,Sydow-Backman, M.,Gustavsson, A.L.,Jendeberg, L. (登録日: 2004-07-01, 公開日: 2004-09-07, 最終更新日: 2024-03-13)

• 主引用文献: Ostberg, T.,Svensson, S.,Selen, G.,Uppenberg, J.,Thor, M.,Sundbom, M.,Sydow-Backman, M.,Gustavsson, A.L.,Jendeberg, L.; A new class of peroxisome proliferator-activated receptor agonists with a novel binding epitope shows antidiabetic effects; J.Biol.Chem., 279:41124-41130, 2004; PubMed: 15258145; DOI: 10.1074/jbc.M401552200

実験手法

X-RAY DIFFRACTION (2.9 Å)