1WK8

Isoleucyl-tRNA synthetase editing domain complexed with the pre-transfer editing substrate analogue, Val-AMS

Summary for 1WK8

• Entry DOI: 10.2210/pdb1wk8/pdb
• Descriptor: Isoleucyl-tRNA synthetase, 5'O-[N-(L-VALYL)SULPHAMOYL]ADENOSINE (3 entities in total)
• Functional Keywords: editing, cp1, isoleucyl-trna synthetase, fidelity, thermus thermophilus, translation, amino acid, structural genomics, riken structural genomics/proteomics initiative, rsgi, nppsfa, national project on protein structural and functional analyses, ligase
• Biological source: Thermus thermophilus
• Cellular location: Cytoplasm: P56690
• Total number of polymer chains: 2
• Total formula weight: 43684.92

Authors

Fukunaga, R.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2004-05-30, release date: 2005-09-27, Last modification date: 2023-10-25)

• Primary citation: Fukunaga, R.,Yokoyama, S.; Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase; J.Mol.Biol., 359:901-912, 2006; PubMed: 16697013; DOI: 10.1016/j.jmb.2006.04.025

Experimental method

X-RAY DIFFRACTION (1.7 Å)