1WAW

Specificity and affinity of natural product cyclopentapeptide inhibitor Argadin against human chitinase

Summary for 1WAW

Entry DOI	10.2210/pdb1waw/pdb
Related	1GUV 1HKI 1HKJ 1HKK 1HKM 1LG1 1LG2 1LQ0 1WB0
Related PRD ID	PRD_000464
Descriptor	CHITOTRIOSIDASE 1, ARGADIN, GLYCEROL, ... (6 entities in total)
Functional Keywords	human chitinase, argadin, cyclopentapeptide inhibitors, chitinase inhibitors, glycosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	50552.43
Authors	Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,van Aalten, D.M.F. (deposition date: 2004-10-28, release date: 2005-01-28, Last modification date: 2023-12-13)
Primary citation	Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,Van Aalten, D.M.F. Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases Chem.Biol., 12:65-, 2005 Cited by PubMed: 15664516 DOI: 10.1016/J.CHEMBIOL.2004.10.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation