1WAW

Specificity and affinity of natural product cyclopentapeptide inhibitor Argadin against human chitinase

1WAW の概要

• エントリーDOI: 10.2210/pdb1waw/pdb
• 関連するPDBエントリー: 1GUV 1HKI 1HKJ 1HKK 1HKM 1LG1 1LG2 1LQ0 1WB0
• 関連するBIRD辞書のPRD_ID: PRD_000464
• 分子名称: CHITOTRIOSIDASE 1, ARGADIN, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: human chitinase, argadin, cyclopentapeptide inhibitors, chitinase inhibitors, glycosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 50552.43

構造登録者

Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,van Aalten, D.M.F. (登録日: 2004-10-28, 公開日: 2005-01-28, 最終更新日: 2023-12-13)

• 主引用文献: Rao, F.V.,Houston, D.R.,Boot, R.G.,Aerts, J.M.F.G.,Hodkinson, M.,Adams, D.J.,Shiomi, K.,Omura, S.,Van Aalten, D.M.F.; Specificity and Affinity of Natural Product Cyclopentapeptide Inhibitors Against Aspergillus Fumigatus, Human and Bacterial Chitinases; Chem.Biol., 12:65-, 2005; PubMed: 15664516; DOI: 10.1016/J.CHEMBIOL.2004.10.013

実験手法

X-RAY DIFFRACTION (1.75 Å)