1W2X

Crystal structure of the carboxyltransferase domain of acetyl- coenzyme A carboxylase in complex with CP-640186

Summary for 1W2X

• Entry DOI: 10.2210/pdb1w2x/pdb
• Related: 1OD2 1OD4 1UYR 1UYS 1UYT 1UYV
• Descriptor: ACETYL-COA CARBOXYLASE, (3R)-1'-(9-ANTHRYLCARBONYL)-3-(MORPHOLIN-4-YLCARBONYL)-1,4'-BIPIPERIDINE (3 entities in total)
• Functional Keywords: transferase, acetyl-coa carboxylase, carboxyltransferase, cp-640186, inhibitor, acc, ct
• Biological source: SACCHAROMYCES CEREVISIAE
• Cellular location: Cytoplasm: Q00955
• Total number of polymer chains: 3
• Total formula weight: 259089.23

Authors

Zhang, H.,Tweel, B.,Li, J.,Tong, L. (deposition date: 2004-07-09, release date: 2004-09-09, Last modification date: 2011-07-13)

• Primary citation: Zhang, H.,Tweel, B.,Li, J.,Tong, L.; Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme a Carboxylase in Complex with Cp-640186; Structure, 12:1683-, 2004; PubMed: 15341732; DOI: 10.1016/J.STR.2004.07.009

Experimental method

X-RAY DIFFRACTION (2.8 Å)