1VYH
PAF-AH Holoenzyme: Lis1/Alfa2
Summary for 1VYH
Entry DOI | 10.2210/pdb1vyh/pdb |
Related | 1FXW |
Descriptor | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT (2 entities in total) |
Functional Keywords | lissencephaly, acetylhydrolase, platelet activacting factor, regulator of cytoplasmic dynein, hydrolase, cell division, mitosis, neurogenesis, cytoskeleton |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm, cytoskeleton: P63005 |
Total number of polymer chains | 20 |
Total formula weight | 723863.97 |
Authors | Tarricone, C.,Perrina, F.,Monzani, S.,Massimiliano, L.,Knapp, S.,Tsai, L.-H.,Derewenda, Z.S.,Musacchio, A. (deposition date: 2004-04-30, release date: 2005-05-26, Last modification date: 2023-12-13) |
Primary citation | Tarricone, C.,Perrina, F.,Monzani, S.,Massimiliano, L.,Kim, M.H.,Derewenda, Z.S.,Knapp, S.,Tsai, L.-H.,Musacchio, A. Coupling Paf Signaling to Dynein Regulation: Structure of Lis1 in Complex with Paf-Acetylhydrolase. Neuron, 44:809-, 2004 Cited by PubMed: 15572112DOI: 10.1016/J.NEURON.2004.11.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
Download full validation report