1VTK
THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE-MONOPHOSPHATE
Summary for 1VTK
| Entry DOI | 10.2210/pdb1vtk/pdb |
| Descriptor | THYMIDINE KINASE, ADENOSINE-5'-DIPHOSPHATE, THYMIDINE-5'-PHOSPHATE, ... (4 entities in total) |
| Functional Keywords | key enzyme in thymidine salvage pathway, additional thymidylate kinase activity, target for anti-herpes viral drugs, transferase |
| Biological source | Herpes simplex virus (type 1 / strain F) |
| Total number of polymer chains | 1 |
| Total formula weight | 37955.01 |
| Authors | Wild, K.,Schulz, G.E. (deposition date: 1997-04-01, release date: 1997-10-22, Last modification date: 2024-02-14) |
| Primary citation | Wild, K.,Bohner, T.,Folkers, G.,Schulz, G.E. The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue. Protein Sci., 6:2097-2106, 1997 Cited by PubMed: 9336833PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
Download full validation report
