1VRH
HRV14/SDZ 880-061 COMPLEX
Summary for 1VRH
Entry DOI | 10.2210/pdb1vrh/pdb |
Descriptor | RHINOVIRUS 14, 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER, ... (5 entities in total) |
Functional Keywords | rhinovirus coat protein, antiviral agents, polyprotein, coat protein, core protein, rna polymerase, hydrolase, thiol protease, myristylation, icosahedral virus, virus |
Biological source | Human rhinovirus 14 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303 |
Total number of polymer chains | 4 |
Total formula weight | 94871.03 |
Authors | Oren, D.A.,Zhang, A.,Arnold, E. (deposition date: 1996-02-26, release date: 1997-02-12, Last modification date: 2024-05-22) |
Primary citation | Oren, D.A.,Zhang, A.,Nesvadba, H.,Rosenwirth, B.,Arnold, E. Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14. J.Mol.Biol., 259:120-134, 1996 Cited by PubMed: 8648640DOI: 10.1006/jmbi.1996.0307 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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