1VRH

HRV14/SDZ 880-061 COMPLEX

1VRH の概要

• エントリーDOI: 10.2210/pdb1vrh/pdb
• 分子名称: RHINOVIRUS 14, 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER, ... (5 entities in total)
• 機能のキーワード: rhinovirus coat protein, antiviral agents, polyprotein, coat protein, core protein, rna polymerase, hydrolase, thiol protease, myristylation, icosahedral virus, virus
• 由来する生物種: Human rhinovirus 14; 詳細
• 細胞内の位置: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 94871.03

構造登録者

Oren, D.A.,Zhang, A.,Arnold, E. (登録日: 1996-02-26, 公開日: 1997-02-12, 最終更新日: 2023-03-15)

• 主引用文献: Oren, D.A.,Zhang, A.,Nesvadba, H.,Rosenwirth, B.,Arnold, E.; Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14.; J.Mol.Biol., 259:120-134, 1996; PubMed: 8648640; DOI: 10.1006/jmbi.1996.0307

実験手法

X-RAY DIFFRACTION (3 Å)