1VRH
HRV14/SDZ 880-061 COMPLEX
1VRH の概要
エントリーDOI | 10.2210/pdb1vrh/pdb |
分子名称 | RHINOVIRUS 14, 2-[4-(2H-1,4-BENZOTHIAZINE-3-YL)-PIPERAZINE-1-LY]-1,3-THIAZOLE-4-CARBOXYLIC ACID ETHYLESTER, ... (5 entities in total) |
機能のキーワード | rhinovirus coat protein, antiviral agents, polyprotein, coat protein, core protein, rna polymerase, hydrolase, thiol protease, myristylation, icosahedral virus, virus |
由来する生物種 | Human rhinovirus 14 詳細 |
細胞内の位置 | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03303 P03303 P03303 P03303 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 94871.03 |
構造登録者 | |
主引用文献 | Oren, D.A.,Zhang, A.,Nesvadba, H.,Rosenwirth, B.,Arnold, E. Synthesis and activity of piperazine-containing antirhinoviral agents and crystal structure of SDZ 880-061 bound to human rhinovirus 14. J.Mol.Biol., 259:120-134, 1996 Cited by PubMed: 8648640DOI: 10.1006/jmbi.1996.0307 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3 Å) |
構造検証レポート
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