1VR2

HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (KDR) KINASE DOMAIN

Summary for 1VR2

• Entry DOI: 10.2210/pdb1vr2/pdb
• Descriptor: PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR KINASE) (2 entities in total)
• Functional Keywords: tyrosine kinase, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cell junction . Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted . Isoform 3: Secreted: P35968
• Total number of polymer chains: 1
• Total formula weight: 36274.74

Authors

Mctigue, M.,Wickersham, J.,Pinko, C.,Showalter, R.,Parast, C.,Tempczyk-Russell, A.,Gehring, M.,Mroczkowski, B.,Kan, C.,Villafranca, J.,Appelt, K. (deposition date: 1998-12-03, release date: 2000-03-15, Last modification date: 2023-11-15)

• Primary citation: McTigue, M.A.,Wickersham, J.A.,Pinko, C.,Showalter, R.E.,Parast, C.V.,Tempczyk-Russell, A.,Gehring, M.R.,Mroczkowski, B.,Kan, C.C.,Villafranca, J.E.,Appelt, K.; Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis.; Structure Fold.Des., 7:319-330, 1999; PubMed: 10368301; DOI: 10.1016/S0969-2126(99)80042-2

Experimental method

X-RAY DIFFRACTION (2.4 Å)