1VPP

COMPLEX BETWEEN VEGF AND A RECEPTOR BLOCKING PEPTIDE

1VPP の概要

• エントリーDOI: 10.2210/pdb1vpp/pdb
• 分子名称: PROTEIN (VASCULAR ENDOTHELIAL GROWTH FACTOR), PROTEIN (PEPTIDE V108) (3 entities in total)
• 機能のキーワード: cystine knot, angiogenesis, vasculogenesis, receptor blocking peptide, growth factor-growth factor inhibitor complex, growth factor/growth factor inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P15692
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 28414.34

構造登録者

Wiesmann, C.,Christinger, H.W.,Cochran, A.G.,Cunningham, B.C.,Fairbrother, W.J.,Keenan, C.J.,Meng, G.,de Vos, A.M. (登録日: 1998-10-09, 公開日: 1999-02-23, 最終更新日: 2023-08-23)

• 主引用文献: Wiesmann, C.,Christinger, H.W.,Cochran, A.G.,Cunningham, B.C.,Fairbrother, W.J.,Keenan, C.J.,Meng, G.,de Vos, A.M.; Crystal structure of the complex between VEGF and a receptor-blocking peptide.; Biochemistry, 37:17765-17772, 1998; PubMed: 9922142; DOI: 10.1021/bi9819327

実験手法

X-RAY DIFFRACTION (1.9 Å)