1VPO
Crystal Structure Analysis of the Anti-testosterone Fab in Complex with Testosterone
Replaces: 1L7SSummary for 1VPO
Entry DOI | 10.2210/pdb1vpo/pdb |
Related | 1L7T |
Descriptor | anti-testosterone (light chain), anti-testosterone (heavy chain), TESTOSTERONE, ... (4 entities in total) |
Functional Keywords | fab fragment, anti-steroid, testosterone complex, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 48024.03 |
Authors | Valjakka, J.M.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. (deposition date: 2004-11-15, release date: 2004-11-23, Last modification date: 2023-08-23) |
Primary citation | Valjakka, J.M.,Hemminki, A.,Niemi, S.,Soderlund, H.,Takkinen, K.,Rouvinen, J. Crystal Structure of an in Vitro Affinity- and Specificity-matured Anti-testosterone Fab in Complex with Testosterone. IMPROVED AFFINITY RESULTS FROM SMALL STRUCTURAL CHANGES WITHIN THE VARIABLE DOMAINS J.Biol.Chem., 277:44021-44027, 2002 Cited by PubMed: 12196551DOI: 10.1074/jbc.M208392200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
Download full validation report